Tuesday 25 December 2012

What Happens During Angioplasty?

What Happens During Angioplasty?

 First, a cardiac catheterization is performed as part of angioplasty. You will receive medication for relaxation, and then the doctor will numb the site where the catheter will be inserted with local anesthesia. Next, a sheath (a thin plastic tube) is inserted into an artery -- usually in your groin, but sometimes in the arm. A long, narrow, hollow tube, called a catheter, is passed through the sheath and guided up the blood vessel to the arteries surrounding the heart. A small amount of contrast material is injected through the catheter and is photographed with an X-ray as it moves through the heart's chambers, valves, and major vessels. From the digital pictures of the contrast material, the doctors can tell whether the coronary arteries are narrowed and whether the heart valves are working correctly. If the decision is made to perform angioplasty, the doctor will move the catheter into the artery with the blockage. He or she will then perform one of the interventional procedures described below. The procedure usually lasts about 1 1/2 to 2 1/2 hours, but the preparation and recovery time add several hours. You may stay in the hospital overnight to be observed by the medical staff. What Types of Interventional Procedures Are Used in Angioplasty? There are several types of interventional procedures which your doctor may use when performing angioplasty. They include:

 * Balloon angioplasty. During this procedure, a specially designed catheter with a small balloon tip is guided to the point of narrowing in the artery. Once in place, the balloon is inflated to compress the fatty matter into the artery wall and stretch the artery open to increase blood flow to the heart. * Stent. A stent is a small metal mesh tube that acts as a scaffold to provide support inside your coronary artery. A balloon catheter, placed over a guide wire, is used to insert the stent into the narrowed coronary artery. Once in place, the balloon tip is inflated and the stent expands to the size of the artery and holds it open. The balloon is then deflated and removed while the stent stays in place permanently. Over a several-week period, your artery heals around the stent. Stents are commonly placed during interventional procedures such as angioplasty to help keep the coronary artery open. Some stents contain medicine and are designed to reduce the risk of reblockage (restenosis). The doctor will determine if this type of stent is appropriate for your type of blockage.

 * Rotoblation. A special catheter, with an acorn-shaped, diamond-coated tip, is guided to the point of narrowing in your coronary artery. The tip spins around at a high speed and grinds away the plaque on your artery walls. The microscopic particles are washed safely away in your blood stream and filtered out by your liver and spleen. This process is repeated as needed to allow for better blood flow. This procedure is rarely used today because balloon angioplasty and stenting have much better results and are technically easier for the cardiologist to perform.

 * Atherectomy. The catheter used in this procedure has a hollow cylinder on the tip with an open window on one side and a balloon on the other. When the catheter is inserted into the narrowed artery, the balloon is inflated, pushing the window against the fatty matter. A blade (cutter) within the cylinder rotates and shaves off any fat that protruded into the window. The shavings are caught in a chamber within the catheter and removed. This process is repeated as needed to allow for better blood flow. Like rotoblation, this procedure is rarely used today.

 * Cutting Balloon. The cutting balloon catheter has a special balloon tip with small blades. When the balloon is inflated, the blades are activated. The small blades score the plaque, then the balloon compresses the fatty matter into the artery wall.

Wednesday 5 December 2012

Nursing & Paramedical Staff Jobs In ESIC, Dec 2012


Online applications are invited by EMPLOYEES STATE INSURANCE CORPORATION (ESIC)for the post of Nursing / Paramedical Examination in Group –C cadre.


  • Name of Post: Staff Nurse Number of Posts: 231Salary: Rs. 9300-34800+4600 GP
  • Name of Post: Occupational Therapist Number of Posts: 01Salary: Rs. 9300-34800+4200 GP
  • Name of Post: Pharmacist ( Allopathic)Number of Posts: 21Salary: Rs. 5200-20200+2800 GP
  • Name of Post: Operation Theatre Assistant Number of Posts: 02Salary: Rs. 5200-20200+2000 GP
  • Name of Post: Laboratory Assistant Number of Posts: 05
    Salary: Rs. 5200-20200+2000 GP
  • Name of Post: Nursing Orderly Number of Posts: 24
    Salary: Rs. 5200-20200+1800 GP
  • Name of Post: Dresser Number of Posts: 13
    Salary: Rs. 5200-20200+1800 GP
  • Name of Post: Laundry Operator Number of Posts: 02
    Salary: Rs. 5200-20200+1800 GP
  • Name of Post: Plaster Technician Number of Posts: 01
    Salary: Rs. 5200-20200+2400 GP
Fee: DD/banker’s Cheque, Money order, postal order, cheques. etc will not be accepted. No fee is required to be paid by Female/SC/ST/Ex.SM/PWD/ESIC Employee/Govt. Employee candidates. Fee once paid will neither be refunded nor adjusted under any circumstances.

1. SC/ST/PWD/ESIC Employees, Female Candidates & Ex. Servicemen: Nil.

2. All other categories: Rs.125/-.
Online Registration of Application: 01-Dec-2012.
Last Date for Applying online and closing of Registration: 21-Dec-2012.
Last Date for Depositing of Fee (through Bank Challan): 24-Dec-2012.
Last Date for Sending of System Generated Application forms (Hard Copy) with required Document: 30-Dec-2012.

How to Apply:
Candidates have to Online Registration as per given instruction in website and send the system generated application form with duly supported with clear / legible attested copies of the relevant certificates and marks statements (in English or Hindi) along with Bank Challan should be sent by Registered post / Speed post or by hand on or before (Last Date) as applicable at the following address:-

Joint. Director (Admn.)EMPLOYEES STATE INSURANCE CORPORATION DIRECTORATE (MEDICAL) DELHI E S I SCHEME: DISPENSARY COMPLEX TILAK VIHAR, (TILAK NAGAR): NEW DELHI – 110018.
More Details: http://www.esic.nic.in/Recruitment/Recdel31212.pdf

Sunday 2 December 2012

dci approved bds mds colleges in andhra pradesh

Sl. No. Name Type Status Seats Sanctioned
1 Govt. Dental College & Hospital,
Afzalganj, Hyderabad – 500012 (A.P.)
Govt. Recognised 40
2 Govt. Dental College & Hospital,
Vijayawada – 520008 (A.P.)
Govt. Recognised 40
3 Army College of Dental Sciences,
Mercury Lines, Trimulgherry, Secunderabad – 500 015 (A.P.).
Private Recognised 40
4 C.V.S. Krishnamurthy Teja Institute of Dental Sciences & Research,
Chandalawada Nagar, Renigunta Road, Tirupati – 517506 (A.P.)
Private Recognised 60
Approved 60 to 100
5 Dr. Sudha & Nageswara Rao Siddhartha Institute of Dental Sciences,
Chinaoutpalli, Gannavaram Mandalam, Krishna Dist. – 521 286 (A.P.)
Private Approved 100
6 G. Pulla Reddy Dental College & Hospital,
Kurnool (A.P.)
Private Approved 50
7 Gitam Dental College,
Gandhinagar Campus, Rushi Konda, Vishakhapatnam – 530045 (Andhra Pradesh)
Private Approved 40
Approved 40 to 100
8 Kamineni Institute of Dental Sciences,
Sreepuram, Narketpally, Nalgonda District – 508 254 (A.P.)
Private Approved 100
9 Lenora Institute of Dental Sciences,
D.No.9-556/1, Visranthipuram, Korukonda Road, Rajahmundry, E.G.Dt. A.P.
Private Approved 60
10 Mamata Dental College,
4-2-161, Police Housing Colony, Opp. Rotary Nagar, Khamam – 507 002 (Andhra Pradesh)
Private Approved 100
11 Meghna Institute of Dental Sciences,
Distt. Nizamabad (Andhra Pradesh)
Private Approved 100
12 MNR Dental College,
Sangareddy, Dist.: Medak, Andhra Pradesh
Private Approved 100
13 Narayana Dental College,
Chinthareddypalem, Nellore – 524 002 (A.P.)
Private Recognised 100
14 Panineeya Mahavidyalaya Institute for Dental Science & Research Centre,
Dilsukhnagar, Ranga Reddy District (A.P.)
Private Approved 100
15 Sibar Institute of Dental Sciences,
Takkellapadu, Guntur – 522 509 (Andhra Pradesh)
Private Recognised 40
Recognised 40 to 100
16 Sree Sai Dental College & Research Institute,
Vill.:Chapuram, Balaga Rural, Dist.: Srikakulam – 532 001 (A.P.)
Private Approved 100
17 Sri Sai College of Dental Surgery,
Opp. Shiv Nagar, Kothrapally, Vikarabad – 501101 (A.P.)
Private Recognised 40
Approved 40 to 100
18 Sri Venkata Sai Institute of Dental Sciences,
H. No.16-2-740/51, Mahabubnagar, Kalyannagar, Gaddiannaram, Hyderabad – 500060 (A.P.)
Private Approved 60
19 St. Joseph Dental College,
Duggirala – 534 004, Eluru, W.G. Dt. A.P.
Private Approved 100
20 Vishnu Dental College,
Kovvada, (V), Vishnupur, Bhimavaram –534202 (A.P.)
Private Approved 100

Saturday 1 December 2012

Dental Colleges in Andhra Pradesh


Army College of Dental Sciences

Established In: 2001
University: N.T.R. University of Health Sciences
UG Courses Available: BDS - 40 Seats
Address: ACDS Nagar (Chennapur - CRPF Road), Post - Jai Jawahar Nagar, , Secunderabad, Andhra Pradesh, 500 087

Dr. Sudha & Nageswara Rao Siddhartha Institute of Dental   Sciences

Year of Establishment: 1975
Affiliated To: N.T.R. University of Health Sciences
UG COURSES: BDS
Adress: Chnaoutpalli, Gannavaram Mandalam, , Krishna District, Andhra Pradesh, 521 286

C.V.S. Krishnamurthy Teja Institute Dental Sciences & Research

Year of Establishment:  
Affiliated To:  
UG COURSE:     BDS- 60 Seats (Recognised), 100 (Approved)
Address: Chandalawada Nagar, Renigunta Road, , Tirupati, Andhra Pradesh, 517 20

G. Pulla Reddy Dental College & Hospital

ESTABLISHED IN: 2006
UNIVERSITY:
 UG Course: 60 seats
Address: Tandrapadu, , Kurnool, Andhra Pradesh, 518 002

Gitam Dental College

Year of Establishment     :      2001
Affiliated To: N.T.R. University of Health Sciences
UG COURSE: BDS
Address: Gandhi Nagar, Rushi Konda, , Visakhapatnam, Andhra Pradesh, 530 045

Kamineni Institute of Dental Sciences

Year of Establishment: 1989
Affiliated To: N.T.R. University of Health Sciences
UG COURSES:     BDS
Address: Sree Puram, Narket Pally, , Nalgonda, Andhra Pradesh, 508 254

Lenora Institute of Dental Science, Visranthipuram

Year of Establishment   :    2008
Affiliated To:  N.T.R. University of Health Sciences
UG COURSES: BDS – 60 seats
Address: D.No. 9-556/1, Visranthipuram, Korukonda Road, E.G. District, Rajahmundry, Andhra Pradesh,

M.N.R. Dental College, Sanga Reddy

Year of Establishment: 2006
Affiliated To: N.T.R. University of Health Sciences
UG COURSES: BDS – 100 seats
Address: M.N.R. Nagar, Narasapur Road, Sanga Reddy, Medak District, Medak, Andhra Pradesh, 502 110

Meghna Institute of Dental Sciences

Year of Establishment: 2006
Affiliated To: N.T.R. University of Health Sciences
UG COURSES: BDS – 100 seats
Address: Mallavaram (V), Varni Road, , Nizamabad, Andhra Pradesh, 503 001

Narayana Dental College

Year of Establishment   :  2006
Affiliated To:  N.T.R. University of Health Sciences
UG COURSES: BDS – 100 seats
Address: Chintareddypalem, , Nellore, Andhra Pradesh, 524 002

Panineeya Mahavidyalaya Institute of Dental Sciences

Year of Establishment: 2003
Affiliated To: N.T.R. University of Health Sciences
UG COURSES: BDS – 100 seats
Address: Road No. 5, Kamala Nagar, Dilsukhnagar, Hyderabad, Andhra Pradesh, 500 060

S.V.S. Institute of Dental Sciences

Year of Establishment   :    2003
Affiliated To: N.T.R. University of Health Sciences
UG COURSES: BDS – 100 seats
Address: Mahabubnagar, , Mahabubnagar, Andhra Pradesh, 509 001

Sibar Institute of Dental Sciences, Pedakakani

Year of Establishment   :    2003
Affiliated To:  N.T.R. University of Health Sciences
UG COURSES: BDS – 100 seats
Address: Takkilapadu, Peddakakani, Guntur, Andhra Pradesh, 522 509

Sri Sai College of Dental Surgery

Year of Establishment:  2001
Affiliated To: N.T.R. University of Health Sciences
UG COURSES: BDS – 100 seats
Address: Shiv Nagar, Kotherupally, R.R. District, Vikarabad, Andhra Pradesh, 501 101

St. Joseph Dental College, West Godavarai

Year of Establishment: 2002
Affiliated To: N.T.R. University of Health Sciences
UG COURSE:  BDS – 100 seats
Address: Duggirala, West Godavarai, Eluru, Andhra Pradesh, 534 007

U H S Dental College

Year of Establishment: 1993
Affiliated To: N.T.R. University of Health Sciences
UG COURSES: BDS – 40 seats
Address: Gunadala, , Vijayawada, Andhra Pradesh, 520 008

Sunday 4 November 2012

World's top univercities for medicine

World's Top 25 Universities For Medicine

Rank Institution Country Academic Employer Citations Score
1 Harvard University  United States  100 100 84 93.6
2 University of Cambridge  United Kingdom  81.7 94.1 74.1 79.9
3 Massachusetts Institute of Technology (MIT)  United States  62.6 83.2 100 79.6
4 University of Oxford  United Kingdom  76.5 90 79.2 78.9
5 Stanford University  United States  74.9 66.3 70.4 72.2
6 Yale University  United States  67.1 55.9 70.3 67.3
7 University of California, Los Angeles (UCLA)  United States  63.5 54.5 67.2 64.1
8 Johns Hopkins University  United States  63.7 29.6 65.7 61.1
9 Imperial College London  United Kingdom  56.9 45.6 63.9 58.6
10 University of California, San Diego (UCSD)  United States  50.6 27 71.2 56.5
11 California Institute of Technology (Caltech)  United States  32.4 38.1 90.8 56.3
12 University of Toronto  Canada  55.7 47.9 54 54.2
13 McGill University  Canada  45.9 63 60.4 53.4
14 Duke University  United States  39.7 57.3 68.6 53
15 The University of Melbourne  Australia  53.2 60.4 49.6 52.5
16 Columbia University  United States  42.8 60.8 62.2 52.4
17 University of California, San Francisco  United States  45.2 24.5 67.5 52.1
18 National University of Singapore (NUS)  Singapore  58.3 57.9 42.3 51.9
19 University of Chicago  United States  41.2 46.4 66.5 51.8
20 The University of Tokyo  Japan  62.8 45.7 38.2 51.3
21 University of Pennsylvania  United States  40.1 48.6 63.5 50.3
22 University of Michigan  United States  39.5 44.3 64.8 50.1
23 Cornell University  United States  40.3 47.2 61 49.3
24 University of Washington  United States  41.4 27.8 64.2 49.2
25 UCL (University College London)  United Kingdom  42.7 46.9 57 48.6

Thursday 1 November 2012

colleges in India


Homeopathy Colleges

A.M. Shaikh Homoeopathic Medical College, Belgaum
Aadya Shri Nigalingeshwar Shikshana Sansthe's S.B.Shirkoli Homoeopathic Medical college, Sankeshwar
Ahmedabad Homoeopathic Medical College, Ahmedabad
Ahmednagar Homoeopathic Medical College, Ahmednagar
Al-Ameen Homoeopathic Medical College, Bijapur
Alvas Homoeopathic Medical College
Anand Homoeopathic Medical College & Research Institute, Anand
Anantrao Kanse Homoeopathic Medical College
Antarbharti Homoeopathic Medical College (Dabha), Nagpur
Anushree Homoeopathic Medical College, Jabalpur
Arihant Homoeopathic Medical College
Assam Govt. Homoeopathic Medical College and Hospital
Athurasramam N.S.S. Homoeopathic Medical College, Kottayam
B.N.M. Homoeopathic Medical College & Hospital, Saharsa
Bakson Homoeopathic Medical College & Hospital, Noida
Baliraja Shikshan Prasarak Mandal's Padmashri Shyamraoji Kadam Homoeopathic Medical College Hospital & Research Centre, New Nanded
Baroda Homoeopathic Medical College, Vadodara
Bengal Homoeopathic Medical College & Hospital
Bhagwan Buddha Homoeopathic Medical College & Hospital, Bangalore
Bharati Vidyapeeth’s Homoeopathic Medical College, Pune
 
Read more: List of Government and Private Homeopathy Colleges in India


Wednesday 31 October 2012

Nursing Colleges in delhi

Nursing Colleges

Anbu College of Nursing
Angel College of Nursing
Annai JKK Sampoorani Ammal College of Nursing
Annai Meenakshi College of Nursing
Annammal College of Nursing
Annapoorna College of Nursing
Annasamy Rajammal College of Nursing
Anushree College of Nursing
Apollo College of Nursing, Kil Ayanambakkam
Apollo College of Nursing
Apollo Gleneagles Nursing College
Aragonda Apollo College of Nursing
Archana College of Nursing
Army College of Nursing
Army Institue Of Nursing
Arun College of Nursing
Arya Nursing College
Ashirvad Nursing & Paramedical Institute
Asian Institute Of Nursing Education
Aswini Nursing College

Tuesday 30 October 2012

List of Nursing Colleges


List of Nursing Colleges In Haryana 2012

Top Nursing Colleges In Haryana, Nursing Courses In Haryana and List of Best Nursing Colleges in Haryana 2012

College Name



Type


State

Amity College Of Nursing - Amity University - Gurgaon
Private Haryana
B D M Nursing College - Jhajjar Private Haryana
Baba Swami Dayal School Of Nursing Private Haryana
Bhai Surender Kumar Memorial Gnm Nursing School Private Haryana
Bharat General Nursing and Midwifery Institute Private Haryana
Bharat Institute Of Nursing Sonepat-gohana Highway Private Haryana
Birender Singh College Of Nursing - Uchana mandi Private Haryana
Chandermukhi School Of Nursing Private Haryana
Christian Hospital , Jagadhri , Yamunanagar Private Haryana
College Of Nursing Private Haryana
Dr Jai Prakash Sharma Memorial College Of Nursing - Yamunanagar Private Haryana
Dr Shanti Yadav School Of Nursing Private Haryana
Everest School Of Nursing Private Haryana
Florence School and College Of Nursing - Ballabgarh Private Haryana
Gandhi School Of Nursing Private Haryana
Geeta Niketan Nursing School Private Haryana
General Hospital of nursing Private Haryana
General Hospital School Of Nursing Private Haryana
Govt Nursing Scool G H Sonepat Private Haryana
Haryana College Of Nursing - Sirsa Private Haryana
Heritage School Of Nursing Private Haryana
K V M Nursing College - Rohtak Private Haryana
Kailash Institute Of Health and Medical Sciences Private Haryana
Kapisthal Institute Of Medical Sciences and Nursing Private Haryana
Khushi School Of Nursing Private Haryana

Friday 26 October 2012

Nursing Colleges in Haryana


 Nursing Colleges
Serial College Name City
1 Maharaja Agrasen Medical College Agroha
2 Rajendra School of Nursing Sirsa
3 Everest School of Nursing Jagadhri
4 Prem Institute of Medical Sciences Baroli
5 Shaheed Baba Deep Singh College of Nursing Ratia
6 Shahed Udham Singh College of Nursing Ratia
7 MSD Institute of Nursing Kalanwali
8 MM School of General Nursing and Midwifery (MMSGNM) Mullana (Ambala)
9 MM College of Nursing (MMCN) Mullana
10 Swami Devi Dayal Group of Professional Institutes Goalpura Village
11 Lord Shiva School of Nursing Sirsa
12 KVM Nursing College Rohtak
13 Lingyas Paradise Nursing College Rohtak
14 Advanced Institute of Pharmacy Aurangabad
15 PGIMS College of Nursing Rohtak
16 Sharbati College of Nursing Mohindergarh
17 Shri Baba Mastnath Nursing Institute Asthal Bohar
18 Birender Singh College of Nursing Uchana Uchana Kalan
19 Kailash Institute of Health and Medical Science Chandimandir
20 Mahabir College of Nursing Ambala
21 Shaheed Bhagat Singh School of Nursing Jagadhri
22 Lingayas Institute of Health Sciences Kanwara Village
23 Swami Devi Dyal College of Nursing Goalpura Village
24 School of Nursing Christian Hospital Jagadhri
25 VED Nursing College Panipat
26 National College of Nursing Barwala
27 State Health and Family Welfare Training Centre Rohtak
28 Multipurpose Health Worker (Male) School Sonepat (Sonipat)
29 Haritage School of Nursing Tohana
30 Chetna School of Nursing Pillukhera
31 MDN School of Nursing Kalayat
32 Rural Nursing Training Institute Sonepat (Sonipat)
33 Holistic Institute of Health Sciences Sirsa
34 Rajendra Institute of Health Sciences Sirsa
35 Govt MPHW (F) Training School Ambala
36 Govt MPHW (F) Training School Narnaul
37 Govt MPHW (F) Training School Bhiwani
38 Govt MPHW (F) Training School Sirsa
39 Govt MPHW (F) Training School Rohtak
40 Govt MPHW (F) Training School Faridabad
41 Govt MPHW (F) Training School Gurgaon
42 Govt MPHW (F) Training School Mewat
43 Lal Bahadur Shastri School of Nursing Yamuna Nagar
44 Swami Vivekanand College of Nursing Jagadhri

Thursday 25 October 2012

Amino Acids

Amino Acids 1.45 MB

Amino Acids:

The building blocks of proteins

pK2
 
pK1
a amino acids because of the a carboxylic and a amino groups

pK 1 and pK 2 respectively pKR is for R group pK’s

pK 1 » 2.2 while pK 2 » 9.4

In the physiological pH range, both carboxylic and amino groups are completely ionized

Amino acids are Ampholytes

They can act as either an acid or a base

They are Zwitterions or molecules that have both a positive and a negative charge

Because of their ionic nature they have extremely high melting temperatures

Amino acids can form peptide bonds
Amino acid residue
peptide units
dipeptides
tripeptides
oligopeptides
polypeptides
 
Proteins are molecules that consist of one or more polypeptide chains 

Peptides are linear polymers that range from 8 to 4000 amino acid residues

There are twenty (20) different naturally occurring amino acids

Linear arrays of amino acids can make a huge number of molecules
Consider a peptide with two amino acids

AA1        AA2
20 x 20 = 400 different molecules
AA2        AA3

20 x 20 = 400 different molecules
20 x 20 x 20 = 8000 different molecules

For 100 amino acid protein the # of possibilities are:

The total number of atoms in the universe is estimated at

Characteristics of Amino Acids
There are three main physical categories to describe amino acids:

1) Non polar “hydrophobic” nine in all

Glycine, Alanine, Valine, Leucine, Isoleucine, Methionine, Proline, Phenylalanine and Tryptophan

2) Uncharged polar, six in all

Serine, Threonine, Asparagine, Glutamine Tyrosine, Cysteine

3) Charged polar, five in all

Lysine, Arginine, Glutamic acid, Aspartic acid, and Histidine

Amino Acids

You must know:

Their names
Their structure
Their three letter code
Their one letter code
Tyrosine, Tyr, Y, aromatic, hydroxyl




Acid - Base properties of amino acids
Isoelectric point: the pH where a protein carries no net electrical charge
For a mono amino-mono carboxylic residue pKi = pK 1 and pKj = pK 2 ; for D and E, pKi = pK 1 and pKj - pK R ; For R, H and K, pKi = K R and pKj = pK 2
Optical activity - The ability to rotate plane - polarized light
Asymmetric carbon atom
Chirality - Not superimposable
Mirror image - enantiomers
(+) Dextrorotatory - right - clockwise
(-) Levorotatory - left counterclockwise
Na D Line passed through polarizing filters.
Stereoisomers
One or many chiral centers
N chiral centers 2 N possible stereoisomers and 2 N-1 are enantiomeric
For N = 2
there are 4 possible sterioisomers
of which 2 are enatiomers
and 2 are diastereomers
Diastereomers are not mirror images and have different chemical properties.
The Fischer Convention
Absolute configuration about an asymmetric carbon
related to glyceraldehyde
(+) = D-Glyceraldehyde
(-) = L-Glyceraldehyde
All naturally occurring amino acids that make up proteins are in the L conformation
In the Fischer projection all bonds in the horizontal direction is coming out of the plane if the paper, while the vertical bonds project behind the plane of the paper
The CORN method for L isomers: put the hydrogen towards you and read off CO R N clockwise around the Ca This works for all amino acids.
An example of an amino acid with two asymmetric carbons
Cahn - Ingold - Prelog system
Can give absolute configuration nomenclature to multiple chiral centers.
Priority
Atoms of higher atomic number bonded to a chiral center are ranked above those of lower atomic number with lowest priority away from you R highest to lowest = clockwise, S highest to lowest = counterclockwise
SH>OH>NH 2>COOH>CHO>CH 2OH>C 6H 5>CH 3>H
The major advantage of the CIP or RS system is that the chiralities of compounds with multiple asymmetric centers can be unambiguously described
Prochiral substituents are distinguishable
Two chemically identical substituents to an otherwise chiral tetrahedral center are geometrically distinct.
Planar objects with no rotational symmetry also have prochariality
Flat trigonal molecules such as aldehydes can be prochiral With the flat side facing the viewer if the priority is clockwise it is called the (a) re face (rectus) else it is the (b) si face (sinistrus).