Sunday, 22 July 2012

Care of the Client Experiencing Preterm Labor

Lecture Twelve: Care of the Client Experiencing Preterm Labor
NURS 2208
T. Dennis RNC, MSN
Preterm Labor (pg 398)
  • Labor that occurs between 20 to 37 completed weeks of pregnancy.
  • Prematurity continues to be the number one perinatal and neonatal problem in the US.
  • Risk factors that play a role in the development of preterm labor include: obstetric, medical, and sociodemographic.
  • The rate of preterm births has not changed much over the last 40 years despite progress in scoring systems, tocolytic drugs, and home monitoring systems.
Risks (pg 398-399)
Maternal Risks:
  • Psychological stress
  • side effects of tocolytics
  • side effects of prolonged bedrest
  • cause of labor (hemorrhage due to placenta previa, etc.)
Fetal-Neonatal risks:
  • Mortality increases
  • respiratory immaturity is the most significant risk to the newborn
  • some circumstances dictate extrauterine life to be more viable than intrauterine life.
Clinical Therapy (pg 399-405)
Symptoms of Preterm labor:
  • Abdominal pain
  • Back pain
  • Pelvic pain
  • Menstrual-like cramps
  • Vaginal bleeding
  • Increased vaginal discharge (may be pink)
  • Pelvic pressure
  • Urinary frequency
  • Diarrhea
Clinical Therapy (pg 399-405)
Diagnostic tools:
  • fFN (fetal fibronectin): an extracelluar matrix protein that is normally found in the fetal membranes and the decidua. After 20 weeks, presence is abnormal until near term.Valuable predicting birth within 7 days of testing.
  • Cervical length: assessed by transvaginal ultrasonography. A cervical length of 3 cms is considered within normal range for the non preterm labor client.
  • Speculum exam determines dilatation of cervix.
  • Fetal monitoring aides in determining contraction pattern.
  • Urinalysis: urinary tract infection is often associated with preterm labor.
Clinical Therapy (pg 399-405)
The following conditions are reasons not to stop preterm labor:
  • Fetal demise
  • Lethal fetal anomaly
  • Severe preeclampsia/eclampsia
  • Hemorrhage (abruptio placentae)
  • Chorioamnionitis
  • Maternal cardiac disease
  • Poorly controlled diabetes mellitis, hypertension, or thyrotoxicosis
  • Fetal maturity
  • Acute fetal distress
Clinical Therapy (pg 399-405)
Goal:
  • To prevent preterm labor from advancing to a point that no longer responds to medical treatment.
Initial management:
  • maintain good uterine profusion
  • detect uterine contractions
  • assess fetal well being
Laboratory studies:
  • CBC , CRP, UA, vaginal, uterine, and amniotic fluid culture
Clinical Therapy (pg 399-405)
  • Hydration is used to decrease the frequency of uterine contractions.
  • Tocolysis is the use of medications to stop labor.
Medications (400)
  • Magnesium Sulfate (MgSO4)
  • Ritodrine (Yutopar)
  • Terbutaline sulfate (Brethine)
  • Nifedipine (Procardia)
  • Betamethasone
  • Dexamethasone
  • Indomethacin
Magnesium Sulfate (MgSO4)
  • A calcium antagonist and central nervous system depressant, relaxes the smooth muscle of the uterus through calcium displacement.
  • Crosses the placenta
  • To control seizures in toxemia of pregnancy due to eclampsia or preeclampsia.
  • 4 Gm bolus IV over 20 to 30 minutes initially then 1 to 2 Gm/hr per infusion pump. Titrated by levels and labor. Serum levels range from 5 to 8 mg/dL to be effective.
  • Side effects include: flushing, HA, nausea, lethargy, metallic taste, hypotension, depressed reflexes, confusion, magnesium toxicity (respiratory depression and arrest).
  • Calcium Gluconate is the antidote (10mg IV push over3 minutes). Calcium chloride may be used.
Magnesium Sulfate (MgSO4) Nursing Interventions
  • Monitor vs every ½ hr and FHR every 15 minutes.
  • Respirations should be above 12/min or she may be toxic.
  • Monitor I&O every hour. Report if urinary output is less than 30ml/h.
  • Check breath and bowel sounds every 4 hours.
  • Assess reflexes prior to initiation of therapy and then every hour. Notify health care provider of change.
  • Weigh daily.
  • Monitor serum Mag levels. Therapeutic level is 5 to 8 mg/dL.
  • Have Calcium gluconate or calcium chloride available as antidote.
  • Observe neonate for 24 to 49 hours for toxicity.
Ritodrine (Yutopar)
  • Beta-sympathomimetic drug acts by stimulating the beta2 receptors in smooth muscle.
  • Ritodrine is the only Beta-sympathomimetic drug approved by FDA for use in preterm labor.
  • Pulmonary edema is a risk.
  • Common therapy is 150 mg in 500cc of fluid and initial rate of 10 to 20 ml per hour.
  • Side effects include: tremors, malaise, dyspnea, tachycardia, chest pain, N&V, pulmonary edema, dysrythmias, ketoacidosis and anaphylactic shock.
Ritodrine (Yutopar) Nursing Interventions
  • Monitor maternal and fetal vs every 15 minutes during IV administration. Report if systolic BP<90 or >140, if diastolic BP< 50 or if pulse >120 bpm.
  • Auscultate breath sounds every 4 hrs. Notify physician if resp rate >30 or if there is a change in quality (wheezes, rales, coughing).
  • Report auscultated cardiac dysrhythmias.
  • Monitor daily weight to assess for fluid overload.
  • Place in trendelenburg position and increase primary IVF’s.
Terbutaline sulfate (Brethine)
  • Sympathomimetic beta2 adrenergic agonist
  • Dosage: 0.25mg SQ initially may repeat every every 15 minutes
  • Action onset is within 15 minutes IV or SQ and 35 to 40 minutes PO.
  • Not approved by FDA for use in preterm labor.
  • May be used with low-dose SQ pumps or PO for maintenance dose.
Terbutaline Nursing Interventions
  • Monitor maternal and fetal vs every 15 minutes during IV administration. Report if systolic BP<90 or >140, if diastolic BP< 50 or if pulse >120 bpm.
  • Auscultate breath sounds every 4 hrs. Notify physician if resp rate >30 or if there is a change in quality (wheezes, rales, coughing).
  • Report auscultated cardiac dysrhythmias.
  • Monitor daily weight to assess for fluid overload.
  • Place in trendelenburg position and increase primary IVF’s.
Nifedipine (Procardia)
  • Calcium Channel blocker
  • Acts by in the myometrial smooth muscle thereby inhibiting contractile activity.
  • May be given orally or sublingually.
  • Side effects include: hypotension, tachycardia, facial flushing and headache.
  • Co-administration with terbutaline may prove effective.
  • Should not be administered with magnesium sulfate due to maternal side effects.
Betamethasone (Celestone, Soluspan)
  • Corticosteroid
  • Dosage: 12 mg IM every 12 hours x 2 doses
  • Given to prevent respiratory distress syndrome in infants by injecting mother prior to delivery to stimulate surfactant production in the fetal lung.
  • Most effective if given at least 24 hr but less than seven days prior to delivery.
  • Onset of action is one to three hours.
  • Side effects include: seizures, HA, vertigo, edema, hypertension, increased sweating, and facial erythema.
Betamethasone Nursing Interventions
  • Observe for respiratory difficulties
  • Maintain accurate I & O records
  • Shake the suspension well, Avoid exposing to excess heat or light.
  • Inject in large muscle mass, not the deltoid, to avoid high incidence of local atrophy.
  • Check blood glucose if used for the diabetic client.
  • Assess lab data for electrolyte values.
Dexamethasone (Decadron)
  • Corticosteroid
  • Dosage: 6 - 12 mg IM every 12 hours x 2 doses
  • Given to prevent respiratory distress syndrome in infantsby injecting mother prior to delivery to stimulate surfactantproduction in the fetal lung.
  • Most effective if given at least 24 hr but less than seven days prior to delivery.
  • Onset of action is one to three hours.
  • Side effects include: seizures, HA, vertigo, edema, hypertension, increased sweating, and facial erythema.
Indomethacin (Indocin)
  • Prostaglandin synthetase inhibitor
  • Inhibits prostaglandin synthesis: closure of patent ductus arteriosis
  • Crosses placental barrier
  • Adverse reactions: dizziness, drowsiness, HA, nausea & vomiting, closure of patent ductus arteriosis (not recommended after 32 wks gestation). Arrythmias, edema
Nursing Assessment and Diagnosis
  • Note presence of predisposing factors:multiple gestation, known cervical incompetence, fetal abnormality, history of pyelonephritis, previous preterm birth, previous preterm labor with termbirth, abdominal trauma.
Diagnosis:
  • Knowledge deficit related to lack of information about causes, identification, and treatment of preterm labor
  • Fear related to early labor and birth
  • Ineffective individual coping related to need for constant attention to pregnancy.
Client Education (pg 402-405)
  • Rest 2 to 3 times a day lying on the left side.
  • Drink 2 to 3 quarts of water each day
  • Avoid caffeine
  • Empty your bladder at least every 2 hours during waking hours
  • Avoid lifting heavy objects
  • Avoid prenatal preparation of the breasts
  • Pace necessary activities to avoid overexertion
  • Eliminate or decrease sexual activity
  • Evaluate contraction activity once or twice a day
  • Report ctxs that occur evey ten minutes for 1 hour.
Signs and Symptoms
  • Uterine contractions that occur every 10 minutes or less with or without pain
  • Mild menstrual like cramps felt low in the abdomen
  • Constant intermittent feelings of pelvic pressure that may feel like the baby pressing down
  • Rupture of membranes
  • Low, dull backache, which may be constant or intermittent
  • A change in vaginal discharge (an increase in amount, a change to more clear and watery, or a pinkish tinge)
  • Abdominal cramping with or without diarrhea
Client Education (pg 402-405)
  • Empty the bladder
  • Lie down tilted toward her side
  • Drink 3 to 4 (8oz) cups of fluid
  • Palpate for uterine contractions, notify care provider if they occur 10 min apart or less for 1 hour
  • Rest for 30 minutes after symptoms have subsided, and gradually resume activity.
  • Call heath care provider if symptoms persist, even if uterine contractions are not palpable.
Hospital Care (pg 404-405)
  • Bedrest
  • Monitor vital signs frequently depending on contraction pattern, medication administration
  • Measure intake and output
  • Continuous EFM of contractions and fetal heart rate
  • Place on left side
  • Keep vaginal exam to a minimum (preferably speculum exam)
  • Keep patient informed of treatments and progress
  • In the event of imminent birth, the client should be offered ongoing explanations to prepare them for the actual birth process and the events following the birth.
Premature Rupture of Membranes (pg 395-397)
  • Spontaneous rupture of membranes prior to the onset of labor is known as premature rupture of membranes (PROM).
  • Preterm PROM is the rupture of membranes before 37 weeks gestation.
  • Prolonged rupture of membranes is rupture more than 24 hours before birth.
  • Cause is unknown.
  • Factors that may contribute to PROM are: incompetent cervix, cervicitis, urinary tract infection, amniocentesis, placenta previa or abruptio, trauma, multiple pregnancy.
  • Preterm PROM accounts for 1/3 of all preterm births.
Premature Rupture of Membranes (pg 395-397)
Maternal Risks:
  • Psychological stress
  • Infection, specifically chorioamnionitis and endometritis
  • side effects of prolonged bedrest
  • cause of PROM (hemorrhage due to abruptio placenta, etc.)
Fetal-Neonatal risks:
  • Mortality increases
  • respiratory distress syndrome is the most significant risk to the newborn
  • Umbilical cord compression.
  • Intrauterine growth restriction, hypoplastic lungs or limb deformities.
Premature Rupture of Membranes (pg 395-397)
Clinical Therapy:
  • Any complain of a gush of fluid or leaking fluid is investigated.
  • Information concerning the time of fluid loss, the color, the consistency, amount and any odor noted.
  • Initial exam may use Nitrazine to test fluid leaking from the introitus or a fern test.
  • If copious amounts of fluid are leaking from the introitus, the diagnosis of PROM is considered confirmed.
  • A sterile speculum exam is done (unless the client is in active labor, a direct digital exam is avoided ).
  • Vaginal cultures should be obtained.
Premature Rupture of Membranes (pg 395-397)
Clinical Therapy:
  • Amniocentesis may be performed to instill dye to detect leakage.
  • Ultrasound may be performed to indicated amniotic fluid index.
  • Fetal well-being should be assessed (amniocentesis for L/S ration, BPP, Fetal Hear Rate pattern.)
  • Management in the absence of infection and gestation <37 weeks is conservative, bedrest, assessing fetal lung maturity.
  • Regular NSTs are performed.
  • Vital signs are assessed every 4 hours.
Premature Rupture of Membranes (pg 395-397)
Laboratory studies:
  • CBC , UA, vaginal and amniotic fluid culture
Initial management:
  • maintain bedrest
  • assess fetal well being (NSTs, BPP)
  • Assess cultures
  • Prophylactic antibiotics may be administered for the first 48 hours. If cultures are positive, antibiotics are continued for 7 days.
  • Cerclage should be removed.
  • Corticosteroid therapy may be instituted but is controversial.
  • Tocolytics are not indicated.
Premature Rupture of Membranes (pg 395-397)
Nursing assessment:
  • Determining duration of the ruptured membranes is key. The risk of infection may be directly related to the time involved. Gestational age is reviewed to prepare for preterm birth. Vital signs and sign of infection are assessed.
Diagnosis:
  • Risk for infection related to premature rupture of membranes.
  • Fear related to early labor and birth
  • Risk for ineffective individual coping relatedto unknown outcome of pregnancy.
  • Impaired gas exchange in the fetus related to compression of the umbilical cord secondary to cord prolapse.
Premature Rupture of Membranes (pg 395-397)
Nursing plan and implementation:
  • Uterine activity and fetal response to labor are evaluated.
  • Vaginal exams are not done unless they are absolutely necessary.
  • Bedrest on left or right side is encouraged.
  • Comfort measures promote rest and relaxation.
  • Hydration is maintained.
  • Education concerning the treatment methods, process and implications of preterm birth are provided along with information about side effects and alternative treatment methods. (vag delivery, csection or demise)
  • Amniotic fluid continues to be produced – no “dry” birth.
Questions?
 

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